The 1852-O Quarter Dollar is a tough date that is incredibly rare in Mint State. In fact, the majority of certified examples grade either XF40 or less. PCGS has certified two Mint State examples, the finest of which is a single PCGS MS63. This date shows the typical strike weakness of a New Orlean product, but some examples are weak at the top of the obverse and the bottom of the reverse, indicating that the dies may have been out of parallel when some coins were struck. This anomaly can be seen on the finest example (illustrated above).
The record price for this date at auction is $126,500, realized in 2007 in a Heritage auction by a PCGS MS63.